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Simian crease

A simian crease is a single palmar crease as compared to two creases in a normal palm. Simian crease occurs in about 1 out of 30 normal people, but is also frequently associated with other conditions such as Down syndrome, Aarskog syndrome or fetal alcohol syndrome.


Review Date: 12/10/2010
Reviewed By: A.D.A.M. Editorial Team: David Zieve, MD, MHA, and David R. Eltz. Previously reviwed by Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine (5/12/2009).
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